84572-73-6

Upstream product

• 74-96-4 ethyl bromide 
• 69923-74-6 monoethyl DL-ethyl-malonate 
• 4244-66-0 3-benzyloxypropionyl chloride 
• 64714-79-0 5-benzyloxy-3-oxo-pentanoic acid ethyl ester 
• 75-03-6 ethyl iodide 
• 3587-60-8 Benzyloxymethyl chloride 
• 607-97-6 ethyl 2-ethyl-3-oxobutanoate 

Downstream Products

• 1310417-57-2 C₂₄H₂₄N₄O₂ 
• 1310417-55-0 5-[2,4-diethyl-5-(2-hydroxy-ethyl)-2H-pyrazol-3-yloxy]isophthalonitrile 
• 1310417-56-1 C₁₆H₂₂N₂O₂ 

Relevant academic research and scientific papers

Enantioselective synthesis of δ-/γ-alkoxy-β-hydroxy- α-alkyl-substituted Weinreb amides via DKR-ATH: Application to the synthesis of advanced intermediate of (-)-brevisamide

A method of preparing stereodefined δ-/γ-alkoxy-β-hydroxy- α-alkyl-substituted Weinreb amides containing two successive hydroxyl-alkyl stereocenters has been developed. Further, this strategy coupled with organo-catalyzed asymmetric epoxidation culminates in the synthesis of a critical intermediate of (-)-brevisamide and its diastereomers.

Comparison of the Non-Nucleoside Reverse Transcriptase Inhibitor Lersivirine with its Pyrazole and Imidazole Isomers

Lersivirine is a potent non-nucleoside reverse transcriptase inhibitor with exceptional mutant resilience. Here, we compare the pharmacological and pharmacokinetic profile of lersivirine with its pyrazole and imidazole isomers and briefly explore the prof

Novel β-lactam acetic acid derivatives

New β-lactam acetic acid derivatives I STR1 wherein R represents alkyl, alkyl substituted with amino, protected amino, mono- or di-alkylamino, hydroxy, protected hydroxy or alkoxy, and alkenyl, and their salts are useful as intermediates for preparing 1-azabicyclo [3.2.0]hept-2-ene antibiotics II STR2 The process for preparing the β-lactam acetic acid derivatives I as well as the overall process which starting from the acids I leads to the antibiotics II are also claimed.