845779-52-4Relevant academic research and scientific papers
Annelation of the thiazole ring to 1,2,4-triazines by tandem A N-AN or SNH-SN H reactions
Mochul'skaya,Andreiko,Kodess,Vasil'eva,Filyakova,Gubaidullin,Litvinov,Sinyashin,Aleksandrov,Charushin
, p. 1279 - 1289 (2007/10/03)
The reactions of 3-aryl-1,2,4-triazines with aromatic thioamides and 4-arylthiosemicarbazides in acetic anhydride at room temperature afforded cyclic products of the tandem nucleophilic addition reactions, viz., tetrahydrothiazolo[4,5-e]-annelated 1,2,4-triazines, in good yields. The latter underwent aromatization in the presence of potassium permanganate.
