845780-46-3

Upstream product

• 845780-44-1 (2S,3S,4R,8S,10R)-1,3-bis(tert-butyldimethylsilanyloxy)-10-[(2S,4R,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]-2,4,8-trimethylundecan-5-one 
• 845780-33-8 (2S,3S,4R,8R,10R)-1,3-bis(tert-butyldimethylsilanyloxy)-10-[(2S,4R,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]-2,4,8-trimethylundec-6-en-5-one 
• 845780-42-9 (4R)-4-benzyl-3-{(2R,3S,4R)-3-hydroxy-4-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]-2-methylpentanoyl}-oxazolidin-2-one 
• 845780-32-7 (3R,4S,5S)-[4,6-bis(tert-butyldimethylsilanyloxy)-3,5-dimethyl-2-oxohexyl]phosphonic acid dimethyl ester 
• 845780-43-0 (4R,5S)-4-{(1S)-1-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]ethyl}-5-methyl[1,3]dioxane-2-thione 
• 845780-30-5 (2R,3R,4R)-4-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]-2-methylpentane-1,3-diol 
• 845780-31-6 (2R,4R)-4-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]-2-methylpentan-1-ol 
• 845780-29-2 (2R)-2-[(2S,4R,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]propan-1-ol 
• 845780-55-4 (S)-2-[(2S,4S,5S)-2-(4-Methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-propionaldehyde 
• 444105-66-2 (3R,4S,5S)-4-[(tert-butyldimethylsilanyl)oxy]-3,5-dimethyltetrahydropyran-2-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 845780-45-2 (2S,3S,4S,5R,8S,10R)-1,3-bis(tert-butyldimethylsilanyloxy)-10-[(2S,4R,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]-2,4,8-trimethylundecan-5-ol 

Downstream Products

• 845780-34-9 (2S,3R,4R,6S,9R,10S,11S,12S)-9,11,13-tris(tert-butyldimethylsilanyloxy)-3-(4-methoxybenzyloxy)-2,4,6,10,12-pentamethyltridecan-1-ol 
• 845780-48-5 1-methoxy-4-{(1R,2S)-2-methyl-1-[(1R,3S,6R,7S,8S,9S)-6,8,10-tris(tert-butyldimethylsilanyloxy)-1,3,7,9-tetramethyldecyl]but-3-enyloxymethyl}benzene 

Relevant academic research and scientific papers

Ring-closing metathesis approach to dictyostatin

(Chemical Equation Presented) An esterification/ring-closing metathesis approach to dictyostatin and discodermolide is introduced. The approach provides for facile fragment coupling of two main segments of these natural products at the C10-C11 alkene with