845782-68-5Relevant academic research and scientific papers
Synthesis and evaluation of a novel series of 2,7-substituted-6-tetrazolyl-1,2,3,4-tetrahydroisoquinoline derivatives as selective peroxisome proliferator-activated receptor γ partial agonists
Morishita, Ko,Ito, Yuma,Otake, Kazuya,Takahashi, Kenji,Yamamoto, Megumi,Kitao, Tatsuya,Ozawa, Shin-Ichiro,Hirono, Shuichi,Shirahase, Hiroaki
, p. 333 - 351 (2021/04/30)
A novel series of 7-substituted-2-[3-(2-furyl)acryloyl]-6-tetrazolyl-1,2,3,4-tetrahydroisoquinoline derivatives were synthesized to clarify structure–activity relationships for peroxisome proliferator-activated receptor γ (PPARγ) partial agonist activity
Facile preparation of oxazole-4-carboxylates and 4-ketones from aldehydes using 3-oxazoline-4-carboxylates as intermediates
Murai, Kenichi,Takahara, Yusuke,Matsushita, Tomoyo,Komatsu, Hideyuki,Fujioka, Hiromichi
supporting information; experimental part, p. 3456 - 3459 (2010/10/01)
(Equation Presented). A novel 2-step synthesis of oxazole-4-carboxylates from aldehydes was developed, which is characterized by the utilization of 3-oxazoline-4-carboxylates as synthetic intermediates. The facile preparation of 4-keto-oxazole derivatives from 3-oxazoline-4-carboxylates based on their interesting reactivity toward Grignard reagents is also described.
