845786-72-3Relevant academic research and scientific papers
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: Synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations
Opa?i?, Ninoslav,Barbari?, Monika,Zorc, Branka,Cetina, Mario,Nagl, Ante,Frkovi?, Danijel,Kralj, Marijeta,Paveli?, Kre?imir,Balzarini, Jan,Andrei, Graciela,Snoeck, Robert,De Clercq, Erik,Rai?-Mali?, Silvana,Mintas, Mladen
, p. 475 - 482 (2007/10/03)
The novel L- and D-amino acid derivatives of hydroxyurea 5a-o were prepared by aminolysis of N-(1-benzotriazolecarbonyl)amino acid amides 4a-o with hydroxylamine. The hydantoin derivatives 6a-e,m,p were synthesized by base-catalyzed cyclization of amides
