845821-92-3

Basic information

• Product Name: 2,2μ Bis(diphenylphosphino)benzophenone
• Synonyms: 2,2μ Bis(diphenylphosphino)benzophenone;DPBP-bidentate phosphine;Bis[2-(diphenylphosphino)phenyl]methanone
• CAS NO: 845821-92-3
• Molecular Formula: C₃₇H₂₈OP₂
• Molecular Weight: 550.575
• Mol File: 845821-92-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 152-156 °C
• Appearance: /
• CAS DataBase Reference: 2,2μ Bis(diphenylphosphino)benzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2μ Bis(diphenylphosphino)benzophenone(845821-92-3)
• EPA Substance Registry System: 2,2μ Bis(diphenylphosphino)benzophenone(845821-92-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 845821-92-3(Hazardous Substances Data)

Upstream product

• 342-23-4 bis(fluorophenyl)methanone 
• 15475-27-1 potassium diphenylphosphine 
• 13102-33-5 2,2'-dimethoxybenzophenone 
• 835-11-0 2,2'-dihydroxybenzophenone 
• 578-57-4 2-bromoanisole 
• 845821-95-6 bis(2-trifluoromethylsulfonyloxyphenyl)methanone 
• 829-85-6 diphenylphosphane 
• 77464-21-2 2-methoxy-α-(2-methoxyphenyl)benzenemethanol 
• 135-02-4 ortho-anisaldehyde 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 62336-24-7 (2-bromophenyl)diphenylphosphane 
• 583-55-1 1-Bromo-2-iodobenzene 

Downstream Products

• 54086-38-3 10-Phenyl-9,10-dihydro-10-λ⁵-acridophosphin-9,10-dion 

Relevant articles and documents

Enhanced Catalytic Activity of Nickel Complexes of an Adaptive Diphosphine-Benzophenone Ligand in Alkyne Cyclotrimerization

Adaptive ligands, which can adapt their coordination mode to the electronic structure of various catalytic intermediates, offer the potential to develop improved homogeneous catalysts in terms of activity and selectivity. 2,2′-Diphosphinobenzophenones have previously been shown to act as adaptive ligands, the central ketone moiety preferentially coordinating reduced metal centers. Herein, the utility of this scaffold in nickel-catalyzed alkyne cyclotrimerization is investigated. The complex [(p-tolL1)Ni(BPI)] (p-tolL1 = 2,2′-bis(di(para-tolyl)phosphino)-benzophenone; BPI = benzophenone imine) is an active catalyst in the [2 + 2 + 2] cyclotrimerization of terminal alkynes, selectively affording 1,2,4-substituted benzenes from terminal alkynes. In particular, this catalyst outperforms closely related bi- and tridentate phosphine-based Ni catalysts. This suggests a reaction pathway involving a hemilabile interaction of the C-O unit with the nickel center. This is further borne out by a comparative study of the observed resting states and DFT calculations.

NOVEL TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL WITH THE COMPLEX

A novel transition metal complex, preferably a ruthenium-phosphine complex or rhodium-phosphine complex, which is effectively usable in various asymmetric syntheses and, in particular, is more effectively usable in the asymmetric hydrogenation of various ketones; and a novel process for producing an optically active alcohol with the complex. The novel transition metal complex includes a ligand obtained by introducing a diarylphosphino group into each of the 2- and 2'-positions of diphenyl ether, benzophenone, benzhydrol, or the like. It preferably further includes an optically active 1,2-diphenylethylenediamine coordinated thereto. The complex preferably is a novel diphosphine-ruthenium-optically active diamine complex or diphosphine-rhodium-optically active diamine complex. The process comprises using the complex as an asymmetric hydrogenation catalyst to conduct the asymmetric hydrogenation of a ketone compound to thereby obtain an optically active alcohol in a high optical purity and a high yield.