845884-66-4

Basic information

• Product Name: Henicosanoic acid (S)-1-henicosanoyloxymethyl-3-((2S,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl ester
• Synonyms: Henicosanoic acid (S)-1-henicosanoyloxymethyl-3-((2S,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl ester
• CAS NO: 845884-66-4
• Molecular Weight: 1229.86
• Mol File: 845884-66-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Henicosanoic acid (S)-1-henicosanoyloxymethyl-3-((2S,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Henicosanoic acid (S)-1-henicosanoyloxymethyl-3-((2S,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl ester(845884-66-4)
• EPA Substance Registry System: Henicosanoic acid (S)-1-henicosanoyloxymethyl-3-((2S,3S,4R,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-propyl ester(845884-66-4)

Safety Data

• Hazardous Substances Data: 845884-66-4(Hazardous Substances Data)

Upstream product

• 2363-71-5 heneicosanoic acid 
• 845884-39-1 (S)-4-((2S,3S,4R,5S,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-butane-1,2-diol 
• 1054627-31-4 (2R,3S,4R,5S,6S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-6-[2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-tetrahydro-pyran 
• 845884-38-0 (2S,3S,4R,5S,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-2-[2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-ethyl]-tetrahydro-pyran-3-ol 
• 845884-37-9 3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-propionic acid (1R,2R,3R)-2,3-bis-benzyloxy-1-benzyloxymethyl-pent-4-enyl ester 
• 100-39-0 benzyl bromide 
• 302800-64-2 3,4,6-tri-O-benzyl-1,2-dideoxy-D-lyxo-hex-1-enitol 
• 111192-54-2 3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-propionic acid 

Relevant articles and documents

RCM-based synthesis of a variety of β-C-glycosides and their in vitro anti-solid tumor activity

(Chemical Equation Presented) The synthesis of a number of biologically relevant C-glycosides has been carried out through the use of an esterification-ring-closing metathesis (RCM) strategy. The required acid precursors were readily prepared via a number of standard chemical transformations followed by dehydrative coupling of these acids with several olefin alcohols 1 to yield the precursor esters 3 in excellent yield. Methylenation of the esters 3 was followed by RCM and in situ hydroboration-oxidation of the formed glycals to furnish the protected β-C-glycosides 6 in good overall yield. Several examples were converted to the corresponding C-glycoglycerolipids 17 and subsequently screened against solid-tumor cell lines for in vitro differential cytotoxicity.