845930-79-2

Usage

Uses

Used in Pharmaceutical Industry:
Benzenemethanamine, 4-bromo-2-fluoro-α-methyl-, (aR)is used as a key intermediate in the synthesis of pharmaceutical drugs for its ability to contribute to the development of complex molecular structures that can be employed in medical treatments.
Used in Research and Development:
In the field of scientific research, Benzenemethanamine, 4-bromo-2-fluoro-a-methyl-, (aR)- is used as a building block for creating new organic compounds, facilitating the discovery and innovation of novel substances with potential applications in various areas of science.
Used in Manufacturing:
Benzenemethanamine, 4-bromo-2-fluoro-α-methyl-, (aR)is utilized in the manufacturing process of various chemical products, leveraging its unique properties to produce materials with specific characteristics required for different applications.
It is crucial to handle Benzenemethanamine, 4-bromo-2-fluoro-α-methyl-, (aR)with care and adhere to proper safety protocols due to its potential hazards, ensuring the safety of both individuals and the environment during its use in various applications.

Upstream product

• 75-16-1 methylmagnesium bromide 
• 105942-08-3 4-bromo-6-fluorobenzonitrile 
• 1034266-11-9 C-azido-C-(2-fluoro-4-bromo-phenyl)-methylamine 

Relevant academic research and scientific papers

3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH

The invention is directed to a formula (I), or a pharmamceutically acceptable salt thereof, wherein R1, R2a, R2b and R3-R7 are herein. The invention is also directed to compositions containing a compound of formula (I) and to the use of such compounds in the inhibition of mutant IDH proteins having a neomorphic activity. The invention is further directed to the use of a compound of formula (I) in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.

Haloalkyl-substituted amides as insecticides and acaricides

The present invention relates to halogen-substituted amide derivatives of the general formula (I)in which R1 to R6, Q1 to Q8, A, V, W, X, Y, n and m are each defined as described in the descriptionand to a process for preparation thereof and to the use th

CB1 RECEPTOR MODULATORS

Compounds of formula (I) suppress the normal signalling activity CB1 receptors, and are thus useful in the treatment of diseases or conditions which are mediated by CB1 receptor signalling activity, such as treatment of obesity and overweight, prevention

Efficient synthesis of chiral phenethylamines: preparation, asymmetric hydrogenation, and mild deprotection of ene-trifluoroacetamides

A mild and efficient route to enantioenriched aryl alkyl amines from ketones has been developed. The first successful synthesis and asymmetric hydrogenation of ene-trifluoroamides from oximes gave highly enantioenriched trifluoroacetamides (94-98% ee). The corresponding phenethyl amides are liberated under mild conditions (K2CO3, MeOH/H2O). In addition, a new application of Josiphos ligands toward the asymmetric hydrogenation of both ene-acetamides and ene-trifluoroacetamides was discovered.