84619-59-0

Basic information

• Product Name: (-)-2-cyclohexyl-2-hydroxyethylamine
• Synonyms: (-)-2-cyclohexyl-2-hydroxyethylamine
• CAS NO: 84619-59-0
• Molecular Weight: 143.229
• Mol File: 84619-59-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (-)-2-cyclohexyl-2-hydroxyethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-2-cyclohexyl-2-hydroxyethylamine(84619-59-0)
• EPA Substance Registry System: (-)-2-cyclohexyl-2-hydroxyethylamine(84619-59-0)

Safety Data

• Hazardous Substances Data: 84619-59-0(Hazardous Substances Data)

Usage

General Description

(-)-2-cyclohexyl-2-hydroxyethylamine is a chemical compound with a cyclohexyl group and a hydroxyethylamine group. It is a chiral molecule, with two enantiomers that are mirror images of each other. (-)-2-cyclohexyl-2-hydroxyethylamine is commonly used in pharmaceutical research and drug development due to its potential as a selective dopamine receptor agonist and antihypertensive agent. It has also been studied for its potential in treating conditions such as Parkinson's disease and schizophrenia. The compound's structure and properties make it interesting for further exploration in the development of new therapeutic drugs.

Upstream product

• 2549-14-6 (R)-2-Amino-1-phenylethanol 
• 133464-06-9 (R)-2-Azido-1-cyclohexyl-ethanol 
• 2043-61-0 cyclohexanecarbaldehyde 
• 133464-07-0 (R)-4-Cyclohexyl-[1,3,2]dioxathiolane 2-oxide 
• 59411-58-4 (R)-1-cyclohexylethane-1,2-diol 
• 4354-47-6 (R)-2-cyclohexyl-2-hydroxyacetonitrile 

Downstream Products

• 185426-16-8 (2R)-(-)-1-tert-butoxycarbonylamino-2-cyclohexylethan-2-ol 

Relevant articles and documents

Enantioselective hydroxylation of nitroalkenes: An organocatalytic approach

An easy hydroxylation of aliphatic nitroalkenes in high yields and enantioselectivities is catalysed by bifunctional thiourea-cinchona alkaloids giving access to optically active nitroalcohols and aminoalcohols as final products. The Royal Society of Chem

A Convenient Route to (R)-α-Hydroxy Carboxylic Acids and (2R)-1-Amino-2-alkanols from (R)-Cyanohydrins

(R)-Cyanohydrins, prepared in good to excellent yields with high optical purity by enzyme-catalyzed addition of hydrogen cyanide to aldehydes in organic solvents, are hydrolyzed with concentrated hydrochloric acid at ambient temperature, usually in very high yield, without any trace of racemization to give (R)-α-hydroxy carboxylic acids.Likewise, no racemization is observed by direct reduction of the (R)-cyanohydrins with lithium aluminium hydride to give (2R)-1-amino-2-alkanols.