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(2-hydroxyethyl)(2-hydroxyhexadecyl)dimethylammonium chloride, also known as dihydroxyethyl cocodimethyl ammonium chloride, is a quaternary ammonium compound that functions as a cationic surfactant and fabric softener. Derived from coconut oil, this water-soluble compound serves as an effective emulsifier and conditioning agent in personal care and cleaning products, enhancing the texture and manageability of hair and skin. However, its potential to cause skin irritation and allergic reactions necessitates careful use and adherence to safety guidelines.

84643-53-8

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84643-53-8 Usage

Uses

Used in Personal Care Industry:
(2-hydroxyethyl)(2-hydroxyhexadecyl)dimethylammonium chloride is used as an emulsifier and conditioning agent for hair and skin care products to improve their texture and manageability, providing a smooth and soft feel to the skin and hair.
Used in Cleaning Products Industry:
In cleaning products, (2-hydroxyethyl)(2-hydroxyhexadecyl)dimethylammonium chloride is used as a fabric softener to make fabrics softer and more pleasant to touch, as well as a surfactant to help in the dispersion of dirt and stains.
Used in Safety and Health Considerations:
While beneficial for its intended applications, (2-hydroxyethyl)(2-hydroxyhexadecyl)dimethylammonium chloride is also used as a cautionary agent due to its potential to cause skin irritation and allergic reactions. It is important to use this chemical with care and follow proper safety guidelines to mitigate any adverse effects on the skin.

Check Digit Verification of cas no

The CAS Registry Mumber 84643-53-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,6,4 and 3 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 84643-53:
(7*8)+(6*4)+(5*6)+(4*4)+(3*3)+(2*5)+(1*3)=148
148 % 10 = 8
So 84643-53-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H44NO2.ClH/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-20(23)19-21(2,3)17-18-22;/h20,22-23H,4-19H2,1-3H3;1H/q+1;/p-1

84643-53-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxyethyl-(2-hydroxyhexadecyl)-dimethylazanium,chloride

1.2 Other means of identification

Product number -
Other names EINECS 283-450-2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:84643-53-8 SDS

84643-53-8Downstream Products

84643-53-8Relevant academic research and scientific papers

A structure-activity study of spermicidal and anti-HIV properties of hydroxylated cationic surfactants

Wong, Yue-Ling,Hubieki,Curfman, Christopher L,Doncel, Gustavo F,Dudding, Travis C,Savle, Prashant S,Gandour, Richard D

, p. 3599 - 3608 (2007/10/03)

The syntheses of 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethylhexadecan-1-aminium chloride [1(16)Cl] and iodide [1(16)I], 2-hydroxy-N,N,N-trimethylhexadecan-1-aminium chloride (6), N-(2-hydroxyethyl)-N,N-dimethylhexadecan-1-aminium chloride (8), N,N-bis(2-hydroxyethyl)-N-methylhexadecan-1-aminium chloride (11), and 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-4-oxahexadecan-1-aminium chloride (14) are reported along with the critical micelle concentrations (cmcs), as measured by conductivity at 25°C, of 1(16)Cl, 1(16)I, 6, 8, 11, and N,N,N-trimethylhexadecan-1-aminium chloride (12). All compounds display spermicidal and virucidal activity. A plot of minimum effective concentration (MEC) in the Sander-Cramer spermicidal assay and cmc shows that 1(16)Cl and 6 have the best spermicidal activity and highest cmcs. Compounds 8, 11, and 1(16)Cl are the most active at 0.05 mg mL-1 against cell-free and cell-associated virus. In conclusion, 1(16)Cl shows the best combination of dual activity against sperm and HIV; it is a promising candidate for further preclinical studies as a topical, contraceptive microbicide.

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