84669-99-8Relevant academic research and scientific papers
PREPARATION OF N-THIOAMIDO-β-LACTAM AND 2-THIOHEXAHYDROPYRIMIDIN-4-ONE DERIVATIVES FROM N-MONOSUBSTITUTED THIOUREAS AND β-HALOACYL HALIDES
Okawara, Tadashi,Nakayama, Kentaro,Furukawa, Mitsuru
, p. 1791 - 1794 (2007/10/02)
The reactions of N-monosubstituted thioureas (1) with β-haloacyl halides (2) were carried out in 5percent NaOH-CH2Cl2 in the presence of a phase transfer catalyst to afford N-thioamido-β-lactams (3 and 5), thioureido acids (4), and 5-hydroxy-2-thiohexahyd
