847036-81-1Relevant articles and documents
Asymmetric total synthesis of (-)-alkaloid 223A and its 6-epimer
Pu, Xiaotao,Ma, Dawei
, p. 4400 - 4405 (2003)
The enantiopure γ-amino alcohols 7 and 18 are prepared by using the diastereoselective Michael addition of lithium N-benzyl (R)-α-methylbenzylamide to α,β-unsaturated esters as a key step. The Michael addition of 7 or 18 to an alkynone 8 followed by an in
An efficient sequential reaction process to polysubstituted indolizidines and quinolizidines and its application to the total synthesis of indolizidine 223A
Zhu, Wei,Dong, Dapeng,Pu, Xiaotao,Ma, Dawei
, p. 705 - 708 (2007/10/03)
(Chemical Equation Presented) The reaction of iodides 1 with δ-chloropropylamines 5 in MeCN assisted with K2CO3 undergoes a sequential SN2/Michael addition/SN2/S N2 reaction process to give polysubsti