547738-47-6

Upstream product

• 85144-28-1 tert-butyl (2E)-hex-2-enoate 
• 101489-01-4 (E)-2-ethyl-2-hexenoic acid 
• 38235-77-7 (R)-N-benzyl-1-phenylethylamine 
• 75-03-6 ethyl iodide 
• 217823-12-6 tert-butyl (3R)-3-aminohexanoate 
• 547738-45-4 2-ethylhex-2-enoic acid tert-butyl ester 

Downstream Products

• 547738-53-4 (5R,6R)-2-(3'-benzyloxy)propyl-3-acetyl-5-ethyl-6-propyl-1,4,5,6-tetrahydropyridine 
• 547738-59-0 (2S,3R,5R,6R)-2-(3'-benzyloxy)propyl-3-acetyl-5-ethyl-6-propylpiperidine 
• 547738-57-8 (2S,3S,5R,6R)-2-(3'-benzyloxy)propyl-3-acetyl-5-ethyl-6-propylpiperidine 
• 547738-51-2 (1'R,2'S)-7-benzyloxy-4-[(2'-hydroxymethyl-1'-propyl)butyl]aminohept-3-en-2-one 
• 847036-81-1 (2S,3R)-3-[benzyl((R)-1-phenylethyl)amino]-2-ethylhexan-1-ol 

Relevant academic research and scientific papers

Studies towards the enantioselective synthesis of 5,6,8-trisubstituted amphibian indolizidine alkaloids via enaminone intermediates

Investigations aimed at the enantioselective total synthesis of indolizidine 223A, a recently described 5,6,8-trisubstituted indolizidine alkaloid from a dendrobatid frog, are described. tert-Butyl (2R,3R)-3-amino-2- ethylhexanoate and its (2S,3R)-diaster

An efficient sequential reaction process to polysubstituted indolizidines and quinolizidines and its application to the total synthesis of indolizidine 223A

(Chemical Equation Presented) The reaction of iodides 1 with δ-chloropropylamines 5 in MeCN assisted with K2CO3 undergoes a sequential SN2/Michael addition/SN2/S N2 reaction process to give polysubsti

Asymmetric total synthesis of (-)-alkaloid 223A and its 6-epimer

The enantiopure γ-amino alcohols 7 and 18 are prepared by using the diastereoselective Michael addition of lithium N-benzyl (R)-α-methylbenzylamide to α,β-unsaturated esters as a key step. The Michael addition of 7 or 18 to an alkynone 8 followed by an in