84705-07-7Relevant academic research and scientific papers
Synthesis of 1,2-benzothiazole-3(2H)-thione 1,1-dioxides by DBU-promoted cyclization of 2-(aminosulfonyl)-N-methylbenzothioamide derivatives
Fujiwara, Daiki,Kobayashi, Kazuhiro
, p. 119 - 128 (2020/01/28)
An efficient method for the preparation of 2-alkyl-1,2-benzothiazole-3(2H)-thione 1,1-dioxides has been developed. Thus, the reaction of 2,N-dilithio derivatives of N-alkylbenzenesulfonamides with methyl isothiocyanate affords 2-[(alkylamino)sulfonyl]-N-methylbenzothioamides, which are treated with a catalytic amount of DBU in refluxing toluene to provide the desired products in moderate to good yields.
