84713-40-6Relevant academic research and scientific papers
Chalaurenol: a Novel Product from Enzymic Oxidation of 2',4,4'-Trihydroxychalcone
Begley, Michael J.,Crombie, Leslie,London, Martin,Savin, John,Whiting, Donald A.
, p. 1319 - 1321 (1982)
Peroxidase enzymes from various sources convert 2',4,4'-trihydroxychalcone (1) into the novel quinol ether of 2-formyl-6-hydroxycoumaranone (6), the structure of which was determined by X-ray diffraction; a biosynthetic pathway is suggested and capillarisin (11) may arise by a similar route.
Metabolism of 2',4,4'-Trihydroxychalcone in Amorpha fruticosa Seedlings; Structure and Role of Chalaurenol, a Novel Heterocyclic Enol Ether formed by Enzymic Oxidation
Begley, Michael J.,Crombie, Leslie,London, A. Martin,Savin, John,Whiting, Donald A.
, p. 2775 - 2782 (2007/10/02)
Amorpha fruticosa seedlings contain two enzymes capable of catalysing reactions of 2',4,4'-trihydroxychalcone.One is a chalcone-flavanone isomerase, which has been purified and occurs as two isozymes.More interestingly, the second is a peroxidase, which oxidises the chalcone (1; R1 = R2 = OH, R3 = H) to a novel labile quinol enol ether, chalaurenol (6), whose structure is established by chemical studies and X-ray diffraction of the 6-O-methyl ether (5).The possible origins and role of chalaurenol in plant metabolism are discussed.
