84714-37-4Relevant academic research and scientific papers
Direct synthesis of N-substituted, functionalized aspartic acids using alkali maleates and amines
Piispanen, Peter S.,Pihko, Petri M.
, p. 2751 - 2755 (2005)
A practical and general one-pot synthesis of mono-N-substituted, functionalized aspartic acids has been developed. The N-substituted aspartic acids are formed directly from alkali maleates and primary amines in hot DMSO. Products from several different primary amines can be prepared chemoselectively in moderate to good yields.
