847358-98-9

Basic information

• Product Name: (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid
• Synonyms: (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid
• CAS NO: 847358-98-9
• Molecular Formula: C₁₄H₁₆BrF₄NO₂
• Molecular Weight: 386.1799528
• Mol File: 847358-98-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid(847358-98-9)
• EPA Substance Registry System: (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid(847358-98-9)

Safety Data

• Hazardous Substances Data: 847358-98-9(Hazardous Substances Data)

Usage

General Description

The chemical (S)-2-((S)-1-(4-bromophenyl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanoic acid is a complex compound with a long name that describes its structure. It is an amino acid derivative with a fluorine-substituted pentanoic acid backbone and a bromophenyl group attached to the alpha carbon. (S)-2-((S)-1-(4-broMophenyl)-2,2,2-trifluoroethylaMino)-4-fluoro-4-Methylpentanoic acid is a chiral molecule, with two stereocenters, and exists as a pair of enantiomers. It may have potential applications in pharmaceuticals or chemical research, as its unique structure and properties could make it useful as a building block for more complex molecules or as a pharmacophore for drug development. Further research and analysis would be needed to fully understand the potential uses and effects of this compound.

Upstream product

• 603142-95-6 (2S)-2-{[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]amino}-4-fluoro-4-methylpentan-1-ol 

Downstream Products

• 1159488-95-5 (S)-2-[(S)-1-(4-bromo-phenyl)-2,2,2-trifluoro-ethylamino]-4-fluoro-4-methyl-pentanoic acid [(S)-1-cyano-2-(4-cyano-2-fluoro-phenyl)-ethyl]-amide 
• 847361-73-3 N²-[(1S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-N¹-[(2R,3S)-2-methyl-4-oxotetrahydrofuran-3-yl]-L-leucinamide 

Relevant articles and documents

Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease

Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease is described. The identified inhibitors bearing an amino nitrile warhead in P1 exhibit low nanomolar in vitro potency against cruzipain. Further SAR in P2 por

CATHEPSIN CYSTEINE PROTEASE INHIBITORS

This invention relates to a novel class of compounds, represented by the formula below, wherein the meanings of G, E, E, n, R1, R2, R3 et R4 are indicated therein, which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

CATHEPSIN CYSTEINE PROTEASE INHIBITORS

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.