847416-23-3

Usage

Isoindole derivative

The compound is derived from the isoindole structure, which is a bicyclic aromatic compound with one six-membered and one five-membered ring.

Trans-4-[(1,1-dimethylethyl)dimethylsilyl]oxy]cyclohexyl group

The compound contains a cyclohexyl group with a trans-4 substitution pattern, which includes a silicon-based substituent ((1,1-dimethylethyl)dimethylsilyl) and an oxygen atom.

Potential applications

The compound may have a wide range of potential applications, but further research and testing are needed to determine its specific properties and uses.

Chemical structure

The compound has a complex structure with multiple rings and functional groups, including an isoindole core, a cyclohexyl group, and a silicon-based substituent.

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 99337-98-1 2-((1R,4R)-4-hydroxycyclohexyl) isoindoline-1,3-dione 
• 50910-54-8 trans-4-aminocyclohexanol hydrochloride 
• 27489-62-9 trans-4-hydroxycyclohexylamine 

Downstream Products

• 950772-07-3 trans-N-(4-ethoxycyclohexyl)phthalimide 
• 919799-78-3 trans-N-(4-propoxycyclohexyl)phthalimide 
• 950772-49-3 trans N-(4-cyclobutyloxycyclohexyl)phthalimide 
• 847416-24-4 trans-2-(4-phenylethyloxy-cyclohexyl)-isoindole-1,3-dione 
• 847416-26-6 trans-2-[4-(5-methyl-2-phenyl-hex-2-enyloxy)-cyclohexyl]-isoindole-1,3-dione 
• 1338051-04-9 2-((trans)-4-(cyclopropylmethoxy)cyclohexyl)isoindoline-1,3-dione 
• 919799-80-7 (trans)-4-(cyclopropylmethoxy)cyclohexanamine 
• 950772-50-6 trans 4-cyclobutyloxycyclohexylamine 
• 950771-77-4 1-(trans-4-ethoxycyclohexyl)piperidin-4-amine 
• 950772-08-4 1-[trans-4-(ethyloxy)cyclohexyl]-4-piperidinone 
• 950772-09-5 trans-1-(4-propoxycylohexyl)-4-piperidone 
• 950772-51-7 trans 1-[4-(cyclobutyloxy)-cyclohexyl]-4-piperidone 

Relevant academic research and scientific papers

SUBSTITUTED PYRROLOTRIAZINES AS PROTEIN KINASE INHIBITORS

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) pyrrolotriazines inhibit protein kinase activity thereby making them useful as anticancer agents.

COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

Compounds of formula (I) or a salt thereof are provided: wherein R4, R5, R6, Q, A, Y and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders, cognitive impairments and Alzheimer's Disease are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.

BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE

Compounds of formula (I), salts and solvates are provided: formula (I), wherein Q, R and R6 are as defined in the claims. Uses of the compounds for therapy, for example in the treatment of psychotic disorders and cognitive impairment, are also disclosed.

4-CYCLOALKYLAMINOPYRAZOLO PYRIMIDINE NMDA/NR2B ANTAGONISTS

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.