847440-52-2Relevant academic research and scientific papers
Tripolide Lactone Ring Derivatives as Immunomodulators and Anticancer Agents
-
Page/Page column 11, (2008/12/09)
Disclosed are compounds based on lactone ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.
METHOD FOR TREATMENT OF INFLAMMATORY DISORDERS USING TRIPTOLIDE COMPOUNDS
-
Page/Page column 15-16, (2008/06/13)
Inflammatory disorders, including obliterative airway disease, renal fibrosis, diabetic nephropathy, and liver fibrosis are treated with immunosuppressive triptolide compounds, in particular triptolide compounds effective to inhibit TGF-β production in a patient afflicted with such a disorder.
