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Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate is a chemical compound characterized by the molecular formula C11H11BrN3O2. It is an organic ester that features a pyridine ring with a bromine atom and a methyl group at distinct positions, offering unique structural and reactivity properties. Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate is recognized for its potential as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, making it a valuable component in the development of new drugs.

847446-55-3

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847446-55-3 Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate serves as a crucial building block for the synthesis of agrochemicals. Its properties allow for the creation of new compounds that can be used in crop protection and other agricultural applications.
Used in Organic Synthesis:
Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate is employed as a versatile reagent in organic synthesis. Its presence in the synthesis process can lead to the formation of a wide range of organic compounds with diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 847446-55-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,7,4,4 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 847446-55:
(8*8)+(7*4)+(6*7)+(5*4)+(4*4)+(3*6)+(2*5)+(1*5)=203
203 % 10 = 3
So 847446-55-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H11BrN2O2/c1-3-16-11(15)9-6-14-5-7(2)4-8(12)10(14)13-9/h4-6H,3H2,1-2H3

847446-55-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 8-bromo-6-methylimidazo[1,2-a]pyridine-2-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:847446-55-3 SDS

847446-55-3Downstream Products

847446-55-3Relevant academic research and scientific papers

Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: Study of microtubule polymerization inhibition and DNA binding

Babu, Bathini Nagendra,Jadhav, Govinda Shivaji,Kadagathur, Manasa,Kiranmai, Gaddam,Nagesh, Narayana,Parimala Devi, G.,Sana, Sravani,Shankaraiah, Nagula,Sigalapalli, Dilep Kumar,Tangellamudi, Neelima D.,Tokala, Ramya,Tripura, Chaturvedula

, (2021/06/30)

Efforts towards the development of potential anticancer agents, a new series of imidazo[1,2-a]pyridine-oxadiazole hybrids were synthesized and evaluated for their in vitro anticancer activity against lung cancer (A549) and prostate cancer (PC-3, DU-145) cell lines. Amongst the compounds tested, 6d showed the highest potency on A549 cells with an IC50 value of 2.8 ± 0.02 μM. Flow cytometric analysis of compound 6d treated A549 cells showed apoptosis induction by annexin-v/PI dual staining assay and the effect of 6d on different phases of cell cycle was also analyzed. Target based studies demonstrated the inhibition of tubulin polymerization by 6d at an IC50 value of 3.45 ± 0.51 μM and its effective binding with CT-DNA. Further, the molecular modelling studies revealed that 6d has a prominent binding affinity towards α/β-tubulin receptor with admirable physico-chemical properties.

Evaluation of the 2-substituent effect on the reactivity of the 8-haloimidazo[1,2-α]pyridine series towards Suzuki-type cross-coupling reaction

Kazock, Jean-Yves,Enguehard-Gueiffier, Cecile,Thery, Isabelle,Gueiffier, Alain

, p. 154 - 159 (2007/10/03)

The purpose of this work was to complete a general study that we initiated on the influence of a 2-substitution on the reactivity of 8-haloimidazo[1 ,2-α]pyridines towards a Suzuki cross-coupling reaction, using conventional reactants in order to obtain e

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