847474-84-4Relevant academic research and scientific papers
Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern
Lange, Jos H.M.,van der Neut, Martina A.W.,Borst, Alice J.M.,Yildirim, Mahmut,van Stuivenberg, Herman H.,van Vliet, Bernard J.,Kruse, Chris G.
experimental part, p. 2770 - 2775 (2010/07/08)
The cannabinoid CB1/CB2 receptor subtype selectivity in the 1,2-diarylimidazole-4-carboxamide series was boosted by fine-tuning its 5-substitution pattern. The presence of the 5-methylsulfonyl group in 11 led to a greater than ～840-f
1 H-imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
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, (2008/06/13)
The present invention relates to a group of novel 1H-imidazole derivatives, to methods for the preparation of these compounds, and to pharmaceutical compositions containing one or more of these compounds as an active component. These 1H-imidazole derivati
