84748-11-8Relevant academic research and scientific papers
PHENOXYPROPYLAMINE COMPOUNDS
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Page 53, (2010/11/29)
The present invention relates to a phenoxypropylamine compound of the formula (I) wherein each symbol is as defined in the specification, an optically active compound thereof or a pharmaceutically acceptable salt thereof and hydrates thereof, which simultaneously show selective affinity for and antagonistic activity against 5-HT1A receptor, as well as 5-HT reuptake inhibitory activity, and can be used as antidepressants quick in expressing an anti-depressive effect.
Analgesic and antiinflammatory properties of 2-benzofuran amidoximes
Riffaud,Dupont,Rene,Royer
, p. 577 - 581 (2007/10/02)
2-Benzofuran carboximidamide and various of its substituted derivatives have been tested for analgesic, anti-inflammatory and ulcerigeneous activity. For comparison, the same tests were performed with 2-naphto[2,1-b]furan carboximidamide, some 3-benzopyrancarboximidamides and 2-furan carboximidamide. Most 2-benzofurancarboximidamides show to have interesting analgesic properties. Some of them are also anti-inflammatories. 3-Methyl-5-bromo-2-benzofurancarboximidamide can be compared to aspirin and phenylbutazone as analgesic and anti-inflammatory respectively; no significant ulcerigeneous effect was noted for this compound.
