84758-58-7

Upstream product

• 54213-21-7 α-Isocyanatobuttersaeure-methylester 
• 84758-57-6 tert-butoxycarbonylamino-2-methyl-propionic acid benzyl ester 
• 84758-56-5 ethyl 2-((tert-butoxycarbonyl)amino)-2-methylpropanoate 
• 84758-55-4 N-(tert-butoxycarbonyl)-α-methylalanine methyl ester 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 87-86-5 Pentachlorophenol 
• 30992-29-1 Boc-Aib-OH 

Relevant academic research and scientific papers

Activated amino acids - structures of anhydride, pentachlorophenyl α-(tert-butyloxycarbonylamino)isobutanoate, and pentachlorophenyl α-(benzyloxycarbonylamino)isobutanoate

anhydride 2O, 1> crystallizes in the space group P 21/n with a = 10.293(4), b = 26.511(6), c = 9.192(4) Angstroem, β = 113.9(3)degry, and Z = 4 (R value for 1246 observed reflections 0.067).The a

SYNTHESE VON 2-METHYLALANIN-PEPTIDEN, DIE pH-ABHAENGIGKEIT IHRER 13C-NMR-SPECTREN UND EINE NEUE METHODE ZUR AUSWERTUNG UEBER CS-DIAGRAMME

The uncommon amino-acid 2-methylalanine (α-aminoisobutiryc acid, Aib) was investigated by 13C-NMR.The chemical shifts of amino- or carboxy-protected derivates of Aib and of protected oligopeptides are discussed with respect to neighbouring groups and amino acids.The pH-dependence of the 13C-NMR spectra of Aib, Aib-Ala, Ala-Aib, Aib-Ala-Aib and Aib-Ala-Aib-Ala-Aib was studied.Using these examples, a new and advantageous method is demonstrated for the first time for the evaluation of NMR titration curves, which uses so-called chemical shift diagrams (CS diagrams).