847585-95-9

Upstream product

• 847585-94-8 6-[(4-isobutylphenyl)ethynyl]-3,4-dihydronaphthalen-1(2H)-one 
• 75-16-1 methylmagnesium bromide 
• 144464-64-2 5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate 
• 3470-50-6 6-Hydroxy-1-tetralone 

Downstream Products

• 847585-96-0 6-[(4-isobutylphenyl)ethyl]-1-methyl-1,2,3,4-tetrahydronaphthalen-1-ol 
• 847585-97-1 7-[2-(4-isobutylphenyl)ethyl]-4-methyl-1,2-dihydronaphthalene 

Relevant academic research and scientific papers

COMPOUND CAPABLE OF BINDING S1P RECEPTOR AND PHARMACEUTICAL USE THEREOF

A compound having an ability to bind to an S1P receptor (particularly EDG-6, preferably EDG-1 and EDG-6), for example, the compound represented by formula (I) of the present invention, a salt thereof, a solvate thereof or a prodrug thereof is useful for prevention and/or treatment of rejection of transplantation, graft-versus-host disease, autoimmune disease, allergic disease and the like. wherein ring A is a cyclic group; ring B is a cyclic group which may have substituent(s); X is a spacer having 1 to 8 atoms in its main chain, etc.; Y is a spacer having 1 to 10 atoms in its main chain, etc.; n is 0 or 1, wherein when n is 0, m is 1 and R1 is a hydrogen atom or a substituent, and wherein when n is 1, m is 0 or an integer of 1 to 7 and R1 is a substituent, and wherein m is 2 or more, R1s are the same or different.