84761-70-6

Basic information

• Product Name: 2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine
• Synonyms: 2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine
• CAS NO: 84761-70-6
• Molecular Formula: C₂₀H₂₃F₂NO₅
• Molecular Weight: 395.3971
• Mol File: 84761-70-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 469.9°Cat760mmHg
• Flash Point: 238°C
• Appearance: /
• Density: 1.202g/cm³
• Vapor Pressure: 5.28E-09mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: 2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine(84761-70-6)
• EPA Substance Registry System: 2,6-Dimethyl-3,5-diethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihy dropyridine(84761-70-6)

Safety Data

• Hazardous Substances Data: 84761-70-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H23F2NO5/c1-5-26-18(24)15-11(3)23-12(4)16(19(25)27-6-2)17(15)13-9-7-8-10-14(13)28-20(21)22/h7-10,17,20,23H,5-6H2,1-4H3

Upstream product

• 71653-64-0 o-difluoromethoxybenzaldehyde 
• 105-45-3 acetoacetic acid methyl ester 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 126335-08-8 4-(2-Difluoromethoxy-phenyl)-2-methyl-5-oxo-5,7-dihydro-furo[3,4-b]pyridine-3-carboxylic acid ethyl ester 
• 89289-93-0 CGP 28392 

Relevant articles and documents

Preparation and properties of ryodipine, an effective antihypertensive agent

A novel effective antihypertensive agent, 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-difluoromethoxyphenyl)-1,4-dihydro pyridine (ryodipine, PP-1466) has been obtained. A method for ryosidine synthesis has been developed, and by products of PP-1466 synthesis have been isolated and identified. Special characteristics (IRS, UVS, NMR, MS) and chromatography data (TLC, HPLC) are cited.