917899-09-3

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 4-(4-bromophenyl)-4-[(3-methoxyphenoxy)methyl]-, 1,1-dimethylethyl ester
• CAS NO: 917899-09-3
• Molecular Formula: C24H30BrNO4
• Molecular Weight: 476.411
• Mol File: 917899-09-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-(4-bromophenyl)-4-[(3-methoxyphenoxy)methyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-(4-bromophenyl)-4-[(3-methoxyphenoxy)methyl]-, 1,1-dimethylethyl ester(917899-09-3)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-(4-bromophenyl)-4-[(3-methoxyphenoxy)methyl]-, 1,1-dimethylethyl ester(917899-09-3)

Safety Data

• Hazardous Substances Data: 917899-09-3(Hazardous Substances Data)

Upstream product

• 150-19-6 O-methylresorcine 
• 913542-80-0 4-(4-bromo-phenyl)-piperidine-4-carboxylic acid 
• 847615-14-9 tert-butyl 4-(4-bromophenyl)-4-cyano-piperidine-1-carboxylate 
• 913542-81-1 4-(4-bromo-phenyl)-piperidine-1,4-dicarboxylic acid mono-(9H-fluoren-9-ylmethyl)ester 

Downstream Products

• 917899-12-8 4-(3-methoxy-phenoxymethyl)-4-[4-(3-methyl-1H-pyrazol-4-yl)-phenyl]-piperidine 
• 917899-11-7 4-[4-(1-dimethylsulphamoyl-3-methyl-1H-pyrazol-4-yl)-phenyl]-4-(3-methoxy-phenoxymethyl)-piperidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

ARYL-ALKYLAMINES AND HETEROARYL-ALKYLAMINES AS PROTEIN KINASE INHIBITORS

The invention provides a compound of the formula (II): or a salt, solvate, tautomer or N-oxide thereof; wherein n is 0 or 1; one of Y1 and Y2 is CH and the other is selected from CH, CR8 and N; q is 0, 1 or 2 provided that q is 0 or 1 when Y1 or Y2 is CR8; R1 is an aryl or heteroaryl group of 5 to 10 ring members; R2a and R3a each are hydrogen, C1-4 hydrocarbyl or C1-4 acyl wherein the hydrocarbyl and acyl moieties are optionally substituted by fluorine, hydroxy, amino, methylamino, dimethylamino or methoxy; or NR2aR3a forms an imidazole group or a saturated monocyclic 4-7 membered heterocyclic group optionally containing a second heteroatom ring member selected from O and N; R18 is hydrogen or methyl; R19 is hydrogen or methyl; R24 is hydrogen or R24, R2a and the intervening nitrogen atom and carbon atoms together form an azetidine, pyrrolidine or piperidine ring; R25 is hydrogen or a C1-4 alkyl group wherein the C1-4 alkyl group is optionally substituted by hydroxy or amino provided that there are at least two carbon atoms between the hydroxy or amino group and the oxygen atom to which R25 is attached; and R4 and R5 each are hydrogen or a substituent as defined in the claims