847666-87-9Relevant academic research and scientific papers
Design, synthesis, and properties of 2′,4′-BNANC: A bridged nucleic acid analogue
Rahman, S. M. Abdur,Seki, Sayori,Obika, Satoshi,Yoshikawa, Haruhisa,Miyashita, Kazuyuki,Imanishi, Takeshi
, p. 4886 - 4896 (2008/09/21)
The novel bridged nucleic-acid analogue 2′,4′-BNANC (2′-O,4′-C-aminomethylene bridged nucleic acid), containing a six-membered bridged structure with an N-O linkage, was designed and synthesized efficiently, demonstrating a one-pot intramolecul
Highly stable pyrimidine-motif triplex formation at physiological pH values by a bridged nucleic acid analogue
Rahman, S. M. Abdur,Seki, Sayori,Obika, Satoshi,Haitani, Sunao,Miyashita, Kazuyuki,Imanishi, Takeshi
, p. 4306 - 4309 (2008/03/11)
Good things come in threes: A novel bridged nucleic acid in which the furanose conformation was locked in the N form by a six-membered bridged moiety containing an N-O bond (see picture) has been developed. Triplex-forming oligonucleotides composed of thi
NOVEL ARTIFICIAL NUCLEIC ACIDS OF N-O BOND CROSSLINKAGE TYPE
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Page/Page column 16; 21, (2010/11/08)
It is intended to provide oligonucleotide analogs usable in, for exmaple, the antisense method which are highly tolerant to enzymes, have a strong and selective binding affinity for a single-stranded RNA and also are highly capable of forming a triple-str
