847730-68-1

Basic information

• Product Name: Benzoic acid, 4-(aminomethyl)-2-fluoro-, methyl ester
• CAS NO: 847730-68-1
• Molecular Formula: C9H10FNO2
• Molecular Weight: 183.182
• Mol File: 847730-68-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(aminomethyl)-2-fluoro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(aminomethyl)-2-fluoro-, methyl ester(847730-68-1)
• EPA Substance Registry System: Benzoic acid, 4-(aminomethyl)-2-fluoro-, methyl ester(847730-68-1)

Safety Data

• Hazardous Substances Data: 847730-68-1(Hazardous Substances Data)

Upstream product

• 85070-57-1 methyl 4-(bromomethyl)-2-fluoro-benzoate 
• 1346125-70-9 4-aminomethyl-2-fluorobenzoic acid hydrochloride 
• 164149-28-4 4-cyano-2-fluorobenzoic acid 
• 175596-01-7 methyl 4-cyano-2-fluorobenzoate 

Downstream Products

• 1191070-13-9 4-(tert-butoxycarbonylaminomethyl)-2-fluorobenzoic acid methyl ester 
• 1289570-77-9 4-({[(2S,3S,4S)-2-(3-Chloro-2-fluoro-phenyl)-3-(4-chloro-2-fluoro-phenyl)-3-cyano-4-(2,2-dimethyl-propyl)-pyrrolidine-1-carbonyl]-amino}-methyl)-2-fluoro-benzoic acid 
• 1289570-78-0 4-({[(2R,3R,4R)-2-(3-chloro-2-fluorophenyl)-3-(4-chloro-2-fluorophenyl)-3-cyano-4-(2,2-dimethylpropyl)pyrrolidine-1-carbonyl]amino}methyl)-2-fluorobenzoic acid 
• 1289571-15-8 2-Fluoro-4-{[(imidazole-1-carbonyl)-amino]-methyl}-benzoic acid methyl ester 

Relevant articles and documents

NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE

Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof.

IMIDAZOLE CARBOXAMIDES

The present invention provides certain imidazole carboxamide derivatives, pharmaceutical compositions thereof, methods of using the same and processes for preparing the same.