847798-80-5Relevant academic research and scientific papers
Synthesis and transformations of alkyl N-(1-cyclohex-3-enyl)carbamates prepared from cyclohex-3-ene carboxylic acid via Curtius rearrangement
Gómez-Sánchez, Elena,Marco-Contelles, José
, p. 1207 - 1219 (2007/10/03)
The Curtius rearrangement of cyclohex-3-ene carboxylic acid using diphenylphosphoryl azide in the presence of triethylamime and ethanol, t-butanol or benzyl alcohol has been described. As a result the synthesis of ethyl, t-butyl or benzyl N-(1-cyclohex-3-enyl)carbamates has been achieved in one pot, in good chemical yield. A series of transformations of benzyl N-(1-cyclohex-3-enyl)carbamate, such as iodination and epoxidation, as well as opening of the corresponding ring epoxide, have been carried out leading to some useful oxygenated cyclohexylamimo building blocks.
