847990-40-3

Basic information

• Product Name: (2-chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-[3-(1H-indol-4-yloxy)-2-methyl-propyl]-amine
• Synonyms: (2-chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-[3-(1H-indol-4-yloxy)-2-methyl-propyl]-amine
• CAS NO: 847990-40-3
• Molecular Weight: 563.062
• Mol File: 847990-40-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-[3-(1H-indol-4-yloxy)-2-methyl-propyl]-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-[3-(1H-indol-4-yloxy)-2-methyl-propyl]-amine(847990-40-3)
• EPA Substance Registry System: (2-chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-[3-(1H-indol-4-yloxy)-2-methyl-propyl]-amine(847990-40-3)

Safety Data

• Hazardous Substances Data: 847990-40-3(Hazardous Substances Data)

Upstream product

• 93118-03-7 2-chloro-3-trifluoromethylbenzaldehyde 
• 2380-94-1 1H-indol-4-ol 
• 612499-61-3 (3-bromopropyl)({ [2-chloro-3-(trifluoromethyl)phenyl]methyl})(2,2-diphenylethyl)amine 

Downstream Products

• 847991-18-8 2-(4-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)-1H-indol-1-yl)acetic acid 
• 847991-29-1 (2-chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-[3-(1-methyl-1H-indol-4-yloxy)-propyl]-amine trifluoroacetate 
• 847990-59-4 (2-chloro-3-trifluoromethyl-benzyl)-(2,2-diphenyl-ethyl)-[(3-(1-methanesulfonyl-1H-indol-4-yl)oxy)-propyl]-amine trifluoroacetate 

Relevant articles and documents

Synthesis and SAR of potent LXR agonists containing an indole pharmacophore

A novel series of 1H-indol-1-yl tertiary amine LXR agonists has been designed. Compounds from this series were potent agonists with good rat pharmacokinetic parameters. In addition, the crystal structure of an LXR agonist bound to LXRα will be disclosed.