848001-50-3

Basic information

• Product Name: Carbamic acid, [(3S)-1-[(1S,2R,4R)-4-[methyl(1-methylethyl)amino]-2-propylcyclohexyl]- 2-oxo-3-pyrrolidinyl]-, phenylmethyl ester
• CAS NO: 848001-50-3
• Molecular Formula: C25H39N3O3
• Molecular Weight: 429.603
• Mol File: 848001-50-3.mol

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(3S)-1-[(1S,2R,4R)-4-[methyl(1-methylethyl)amino]-2-propylcyclohexyl]- 2-oxo-3-pyrrolidinyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(3S)-1-[(1S,2R,4R)-4-[methyl(1-methylethyl)amino]-2-propylcyclohexyl]- 2-oxo-3-pyrrolidinyl]-, phenylmethyl ester(848001-50-3)
• EPA Substance Registry System: Carbamic acid, [(3S)-1-[(1S,2R,4R)-4-[methyl(1-methylethyl)amino]-2-propylcyclohexyl]- 2-oxo-3-pyrrolidinyl]-, phenylmethyl ester(848001-50-3)

Safety Data

• Hazardous Substances Data: 848001-50-3(Hazardous Substances Data)

Upstream product

• 848001-48-9 benzyl (S)-1-[(1S,2R,4R)-4-amino-2-propylcyclohexyl]-2-oxopyrrolidin-3-ylcarbamate 
• 848001-45-6 {(3S)-1-[(1S,2R,4R)-4-tert-butoxycarbonylamino-2-propylcyclohexyl]-2-oxopyrrolidin-3-yl}carbamic acid benzyl ester 
• 848001-44-5 C₂₈H₄₆N₃O₅S⁽¹⁺⁾*I^(1-) 
• 848001-43-4 (1R,3R,4S)-[4-((2S)-2-benzyloxycarbonylamino-4-methylsulfanylbutyrylamino)-3-propylcyclohexyl]carbamic acid tert-butyl ester 
• 847956-54-1 (1R,3R,4S)-(4-amino-3-propyl-cyclohexyl)carbamic acid tert-butyl ester 
• 847956-53-0 (1R,3S,4S)-(4-benzyloxycarbonylamino-3-propenylcyclohexyl)carbamic acid tert-butyl ester 
• 50-00-0 formaldehyd 
• 847955-78-6 tert-butyl (1R,2S,5R,7R/S)-2-(benzyloxycarbonylamino)-7-hydroxy-6-aza-bicyclo[3.2.1]octane-6-carboxylate 
• 746670-91-7 (1R,2S,5R)-tert-butyl 2-(benzyloxycarbonylamino)-7-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate 
• 67-64-1 acetone 

Downstream Products

• 847998-94-1 C₂₅H₃₆ClN₅O 
• 848001-51-4 (S)-3-amino-1-[(1S,2R,4R)-4-(isopropyl(methyl)amino)-2-propylcyclohexyl]pyrrolidin-2-one 

Relevant articles and documents

Discovery of a potent and orally bioavailable dual antagonist of CC chemokine receptors 2 and 5

We describe the hybridization of our previously reported acyclic and cyclic CC chemokine receptor 2 (CCR2) antagonists to lead to a new series of dual antagonists of CCR2 and CCR5. Installation of a γ-lactam as the spacer group and a quinazoline as a benz

Cyclic derivatives as modulators of chemokine receptor activity

The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the treatment of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.