84802-40-4

Basic information

• Product Name: 1-(1-cyano-2-ethoxy-2-oxoethyl)-4-methylpyridinium
• CAS NO: 84802-40-4
• Molecular Formula: C₁₁H₁₂N₂O₂
• Molecular Weight: 205.2326
• Mol File: 84802-40-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1-cyano-2-ethoxy-2-oxoethyl)-4-methylpyridinium(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-cyano-2-ethoxy-2-oxoethyl)-4-methylpyridinium(84802-40-4)
• EPA Substance Registry System: 1-(1-cyano-2-ethoxy-2-oxoethyl)-4-methylpyridinium(84802-40-4)

Safety Data

• Hazardous Substances Data: 84802-40-4(Hazardous Substances Data)

Usage

General Description

1-(1-cyano-2-ethoxy-2-oxoethyl)-4-methylpyridinium is a chemical compound with potential applications in the field of organic synthesis and pharmaceuticals. It is a pyridinium salt with a cyano group and an ethoxy-oxoethyl group attached to the pyridine ring. The presence of these functional groups gives the compound unique reactivity and potential for use as a reagent in organic chemical reactions. Additionally, the methyl group attached to the pyridinium ring provides further opportunities for functionalization and modification of the compound for specific applications. Overall, the unique structure and reactivity of 1-(1-cyano-2-ethoxy-2-oxoethyl)-4-methylpyridinium make it a versatile and potentially valuable chemical in various chemical and pharmaceutical applications.

Upstream product

• 5349-28-0 thiocyanato-acetic acid ethyl ester 
• 129170-15-6 1-ethoxycarbonylmethyl-4-methylpyridinium chloride 

Relevant articles and documents

Preparation of New Nitrogen-Bridged Heterocycles. 42.1 Synthesis and the Reaction of Pyridinium N-Ylides Using Bifunctional Ethyl Thiocyanatoacetates

Various pyridinium (monosubstituted methylide)s were smoothly attacked to the cyano group in ethyl thiocyanatoacetate or ethyl 2-thiocyanatopropionate to afford the corresponding pyridinium (substituted cyanomethylide)s in low-to-moderate yields, while pyridinium (unsubstituted amidate)s reacted with the ester carbonyl group in the same reagents to give pyridinium (thiocyanatoaceto)- or (2-thiocyanatopropiono)amidates in considerable yields. The 1,3-dipolar cycloadditions of some pyridinium (unsymmetrically substituted cyanomethylide)s with dimethyl acetylenedicarboxylate (DMAD) in various solvents afforded only dimethyl 3-cyanoindolizine-1,2-dicarboxylate, except a few examples. On the other hand, the treatment of pyridinium (thiocyanatoaceto)- or (2-thiocyanatopropiono)amidates with a strong base, such as potassium t-butoxide, gave new bicyclic mesoionic compounds, N-[2-(1,3,4-thiadiazolo(3,2-a]pyridinio)]acetamidate derivatives, in moderate yields. The intermediacy of N-[1-(2-thiocyanatopyridinio)]acetamidates in the formation reactions of the latter compounds was also proven by independent syntheses.