84802-41-5

Basic information

• Product Name: C₁₂H₁₄N₂O₂
• Synonyms: C₁₂H₁₄N₂O₂
• CAS NO: 84802-41-5
• Molecular Weight: 218.255
• Mol File: 84802-41-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₄N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₄N₂O₂(84802-41-5)
• EPA Substance Registry System: C₁₂H₁₄N₂O₂(84802-41-5)

Safety Data

• Hazardous Substances Data: 84802-41-5(Hazardous Substances Data)

Upstream product

• 5349-28-0 thiocyanato-acetic acid ethyl ester 
• 129170-16-7 1-Ethoxycarbonylmethyl-3,5-dimethyl-pyridinium; chloride 

Relevant articles and documents

Preparation of New Nitrogen-Bridged Heterocycles. 42.1 Synthesis and the Reaction of Pyridinium N-Ylides Using Bifunctional Ethyl Thiocyanatoacetates

Various pyridinium (monosubstituted methylide)s were smoothly attacked to the cyano group in ethyl thiocyanatoacetate or ethyl 2-thiocyanatopropionate to afford the corresponding pyridinium (substituted cyanomethylide)s in low-to-moderate yields, while pyridinium (unsubstituted amidate)s reacted with the ester carbonyl group in the same reagents to give pyridinium (thiocyanatoaceto)- or (2-thiocyanatopropiono)amidates in considerable yields. The 1,3-dipolar cycloadditions of some pyridinium (unsymmetrically substituted cyanomethylide)s with dimethyl acetylenedicarboxylate (DMAD) in various solvents afforded only dimethyl 3-cyanoindolizine-1,2-dicarboxylate, except a few examples. On the other hand, the treatment of pyridinium (thiocyanatoaceto)- or (2-thiocyanatopropiono)amidates with a strong base, such as potassium t-butoxide, gave new bicyclic mesoionic compounds, N-[2-(1,3,4-thiadiazolo(3,2-a]pyridinio)]acetamidate derivatives, in moderate yields. The intermediacy of N-[1-(2-thiocyanatopyridinio)]acetamidates in the formation reactions of the latter compounds was also proven by independent syntheses.