84803-41-8Relevant academic research and scientific papers
Beyond the Tebbe Olefination: Direct Transformation of Esters into Ketones or Alkenes
Dom?alska-Pieczykolan, Anna M.,Furman, Bart?omiej
, p. 730 - 736 (2020)
A direct, effective, and operationally simple transformation of esters into ketones or alkenes by the exclusive action of Tebbe's reagent has been developed. The transformation utilizes the dual character of Tebbe's reagent as both a methylenation agent and a rearrangement catalyst in the reaction of a wide range of substituted vinyl ethers. The resulting transformation involves sequential methylenation and rearrangement reactions and it offers a high degree of selectivity toward the synthesis of ketones or alkenes. The scope and limitations of the developed methods have been also examined.
Scope and Limitations of Aliphatic Friedel-Crafts Alkylations. Lewis Acid Catalyzed Addition Reactions of Alkyl Chlorides to Carbon-Carbon Double Bonds
Mayr, Herbert,Striepe, Wilhelm
, p. 1159 - 1165 (2007/10/02)
Lewis acid catalyzed addition reactions of alkyl halides 1 with unsaturated hydrocarbons 2 have been studied. 1:1 addition products 3 are formed if the addends 1 dissociate faster than the corresponding products 3; otherwise, polymerization of 2 takes place.For reaction conditions under which 1 and 3 exist mainly undissociated, solvolysis constants of model compounds can be used to predict the outcome of any such addition reactions if systems with considerable steric hindrance are excluded.
