848044-20-2

Upstream product

• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 848044-18-8 tert-butyl 3-chloro-O-methyl-D-tyrosinate 

Downstream Products

• 848044-28-0 tert-butyl (2E,5S,6R,7E)-5-[(2S)-2-{[(2R)-3-({3-chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-methyl-D-tyrosyl}amino)-2-methylpropanoyl]oxy}-4-methylpentanoyloxy]-6-methyl-8-phenylocta-2,7-dienoate 
• 1027041-92-4 (2E,7E)-(5S,6R)-5-((S)-2-{(R)-3-[(R)-3-(3-Chloro-4-methoxy-phenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionylamino]-2-methyl-propionyloxy}-4-methyl-pentanoyloxy)-6-methyl-8-phenyl-octa-2,7-dienoic acid 
• 848044-27-9 tert-butyl (2S)-2-{[(2R)-3-({3-chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-methyl-D-tyrosyl}amino)-2-methylpropanoyl]oxy}-4-methylpentanoate 
• 848044-13-3 (2S)-2-{[(2R)-3-({3-chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-methyl-D-tyrosyl}amino)-2-methylpropanoyl]oxy}-4-methylpentanoic acid 
• 182486-27-7 (2E,7E)-(5S,6R)-5-((S)-2-{(R)-3-[(R)-2-Amino-3-(3-chloro-4-methoxy-phenyl)-propionylamino]-2-methyl-propionyloxy}-4-methyl-pentanoyloxy)-6-methyl-8-phenyl-octa-2,7-dienoic acid 
• 124689-64-1 cryptophycin C 
• 848044-14-4 3-chloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-methyl-D-tyrosine 

Relevant academic research and scientific papers

Total synthesis of cryptophycin 3

The depsipeptide cryptophycin 3 (5) and the cryptophycin analogue 43 were prepared from the corresponding four subunits, The tripeptide analogue 34 was acquired from the starting amino ester 33, which contains fragments D and C. After extension at the car