848073-34-7Relevant academic research and scientific papers
CYCLIC AMINE COMPOUNDS
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Page/Page column 49; 51, (2011/10/19)
Problems to be solved are to provide novel low-molecular compounds which exhibit calcium receptor antagonist activity, and which are highly safe and orally administrable. As a means for solving the problems, compounds having the Formula (I) or pharmaceuti
Discovery and structure-activity relationships of 2-benzylpyrrolidine- substituted aryloxypropanols as calcium-sensing receptor antagonists
Yang, Wu,Wang, Yufeng,Roberge, Jacques Y.,Ma, Zhengping,Liu, Yalei,Lawrence, R. Michael,Rotella, David P.,Seethala, Ramakrishna,Feyen, Jean H. M.,Dickson Jr., John K.
, p. 1225 - 1228 (2007/10/03)
A structure-activity relationship study of the amine portion of the calcilytic compound NPS-2143 resulted in the discovery of substituted 2-benzylpyrrolidines as replacements for the 1,1-dimethyl-2-naphthalen-2-yl- ethylamine. When compared to NPS-2143, a
