848185-40-0 Usage
Uses
Used in Oncology:
Mesna is utilized as a detoxifying agent in cancer treatment to safeguard patients from the harmful side effects of specific chemotherapy drugs. It is used for:
1. Preventing Bladder Damage:
(5-(Methylsulfonyl)pyridin-2-yl)MethanaMine is used as a protective agent for preventing bladder damage caused by the toxic metabolites of chemotherapy drugs ifosfamide and cyclophosphamide.
2. Treating Hemorrhagic Cystitis:
(5-(Methylsulfonyl)pyridin-2-yl)MethanaMine is used as a therapeutic agent for treating hemorrhagic cystitis, a condition often induced by the cytotoxic effects of chemotherapy.
3. Enhancing Chemotherapy Safety and Tolerability:
(5-(Methylsulfonyl)pyridin-2-yl)MethanaMine is used as a supportive component in chemotherapy regimens to improve the safety and tolerability of potent cancer treatments, ensuring that patients can receive effective cancer therapy with reduced risk of severe side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 848185-40-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,1,8 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 848185-40:
(8*8)+(7*4)+(6*8)+(5*1)+(4*8)+(3*5)+(2*4)+(1*0)=200
200 % 10 = 0
So 848185-40-0 is a valid CAS Registry Number.
848185-40-0Relevant academic research and scientific papers
BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME
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Paragraph 0094, (2019/05/10)
The present invention discloses a biaryl urea RORγt inhibitor, and specifically relates to a biaryl urea derivative, as represented by formula I, with an RORγt inhibiting activity, and a preparation process thereof, and a pharmaceutical composition comprising the compound. Further disclosed is use of the compound for treating an RORγt-related disease.
