84819-29-4Relevant academic research and scientific papers
Sulfonic acid supported on hydroxyapatite-encapsulated-γ-Fe 2O3 nanocrystallites as a magnetically separable catalyst for one-pot reductive amination of carbonyl compounds
Deng, Jia,Mo, Li-Ping,Zhao, Fei-Yang,Hou, Lan-Lan,Yang, Li,Zhang, Zhan-Hui
, p. 2576 - 2584 (2011/10/18)
A novel, environmentally friendly procedure has been developed for the preparation of secondary or tertiary amines by one-pot reductive amination of carbonyl compounds using sodium borohydride in the presence of a magnetically recoverable sulfonic acid supported on hydroxyapatite-encapsulated-γ- Fe2O3 [γ-Fe2O3@HAP-SO 3H] at room temperature. The catalyst was easily separated from the reaction mixture by applying an external magnet and reused for six cycles without significant loss of catalytic activity.
Qualitative analysis of the stability of the oxazine ring of various benzoxazine and pyridooxazine derivatives with proton nuclear magnetic resonance spectroscopy
Moloney,Craik,Iskander
, p. 692 - 697 (2007/10/02)
A series of 3,4-dihydro-1,3-benzoxazine and 3,4-dihydro-1,3-pyridooxazine derivatives was synthesized, and the hydrolysis of the derivatives was studied with proton nuclear magnetic resonance spectroscopy. The oxazine derivatives underwent various degrees of hydrolysis when H2O was added to dimethyl sulfoxide solutions of the compounds. The rates and extents of decomposition of the oxazine ring systems depended on the electronic effects of substituents within the molecules. Examination of the proton nuclear magnetic resonance spectra that were generated during decomposition of the oxazines and trends in stability of the oxazine derivatives suggest the formation of an intermediate in the hydrolysis mechanism.
Antioxidant-Based Inhibitors of Leukotriene Biosynthesis. The Discovery of 6--1-propen-3-yl>-2,3-dihydro-5-benzofuranol, a Potent Topical Antiinflammatory Agent
Hammond, Milton L.,Zambias, Robert A.,Chang, Michael N.,Jensen, Norman P.,McDonald, John,et al.
, p. 909 - 918 (2007/10/02)
The leukotrienes, metabolites of arachidonic acid produced through the action of the enzyme 5-lipoxygenase, are important mediators of immediate hypersensitivity and inflammation.Among the variety of diseases in which the leukotrienes may play a symptomat
Hydroxybenzylamino derivatives as anti-inflammatory agents
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, (2008/06/13)
Hydroxybenzylamino derivatives have been prepared from an appropriate hydroxybenzaldehyde and an amine followed by reduction. These compounds are found to be active topical anti-inflammatory agents.
