848307-25-5

Usage

Class of chemical

Esters

Derivative

Pyrrolidinecarboxylic acid

Stereochemistry

3R,4S configuration

Usage

Pharmaceutical research and drug development, synthesis of organic compounds, key building block for production of new molecules with enhanced biological activity.

Upstream product

• 848307-24-4 (3R,4S)-3-hydroxymethyl-4-phenylpyrrolidine 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 848307-24-4 (3R,4S)-3-hydroxymethyl-4-phenylpyrrolidine 
• 848307-26-6 (3R,4S)-3-formyl-4-phenyl-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

NOVEL SPIROTROPANE COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY

Compounds according to formula (I): wherein the radical R2 represents a hydrogen atom or one of the following structures: R, and R7_9are as herein defined, and wherein ring A represents a 5 or 6 membered heteroring involvi

Spirohydantoin compounds and methods for the modulation of chemokine receptor activity

Novel compounds represented by formula (I): wherein R1, R2, R3 and R4 are as defined herein, and pharmaceutically acceptable salts, hydrates and solvates thereof, are useful for the modulation of CCR5 chemokine

SPIRO COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY

Compounds of formula I insert formula I from claim 1 wherein X, Y, Z, W, R1 and R2 as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity.