848307-24-4

Usage

Uses

Used in Medicinal Chemistry:
((3R,4S)-4-Phenylpyrrolidin-3-yl)methanol is used as a precursor in the synthesis of various pharmaceuticals due to its unique structure and properties. It plays a crucial role in the development of new drugs and therapeutic agents, contributing to advancements in medicinal chemistry.
Used in Academic Research:
In the field of academic research, ((3R,4S)-4-Phenylpyrrolidin-3-yl)methanol is utilized for studying organic chemistry and drug design. Its specific structure and properties make it a valuable subject for research, potentially leading to new insights and discoveries in the realm of chemical synthesis and pharmaceutical development.
Used in Pharmaceutical Industry:
((3R,4S)-4-Phenylpyrrolidin-3-yl)methanol is used as a key intermediate in the production of pharmaceuticals, particularly those targeting specific medical conditions. Its unique chiral properties allow for the creation of enantiomerically pure compounds, which can have distinct biological activities and therapeutic effects.
Used in Drug Design:
((3R,4S)-4-Phenylpyrrolidin-3-yl)methanol is employed as a building block in drug design, allowing chemists to create novel molecules with specific biological targets. Its chiral nature enables the development of enantioselective drugs, which can exhibit improved efficacy and reduced side effects compared to their racemic counterparts.

InChI:InChI=1/C11H15NO/c13-8-10-6-12-7-11(10)9-4-2-1-3-5-9/h1-5,10-13H,6-8H2/t10-,11-/m1/s1

Upstream product

• 848307-25-5 (3R,4S)-tert-butyl 3-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate 
• 5153-67-3 nitrostyrene 
• 221141-87-3 [(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methanol 

Downstream Products

• 848307-25-5 (3R,4S)-tert-butyl 3-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate 

Relevant academic research and scientific papers

Antinociceptive and antidepressant-like action of endomorphin-2 analogs with proline surrogates in position 2

In our efforts to develop new candidate drugs with antinociceptive and/or antidepressant-like activity, two novel endomorphin-2 (EM-2, Tyr-Pro-Phe-Phe-NH2) analogs, containing proline surrogates in position 2 were synthesized using commercially

Diastereodivergent Access to Syn and Anti 3,4-Substituted β-Fluoropyrrolidines: Enhancing or Reversing Substrate Preference

A practical diastereodivergent access to β-fluoropyrrolidines with two adjacent stereocenters has been demonstrated, by either enhancing or completely reversing the substrate control, in the diastereoselective fluorination of a series of diverse pyrrolidi

NOVEL SPIROTROPANE COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY

Compounds according to formula (I): wherein the radical R2 represents a hydrogen atom or one of the following structures: R, and R7_9are as herein defined, and wherein ring A represents a 5 or 6 membered heteroring involvi

Spirohydantoin compounds and methods for the modulation of chemokine receptor activity

Novel compounds represented by formula (I): wherein R1, R2, R3 and R4 are as defined herein, and pharmaceutically acceptable salts, hydrates and solvates thereof, are useful for the modulation of CCR5 chemokine

SPIRO COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY

Compounds of formula I insert formula I from claim 1 wherein X, Y, Z, W, R1 and R2 as defined herein, or pharmaceutically acceptable salts, hydrates or solvates thereof, are useful for the modulation of CCR5 chemokine receptor activity.