848357-91-5 Usage
Indole ring
A core structure consisting of a 5-membered nitrogen-containing aromatic ring fused with a 6-membered aromatic ring.
Carboxylic acid group
A functional group (-COOH) present in the compound, which contributes to its acidity and may participate in hydrogen bonding and other interactions.
Thienopyrazole group
A 5-membered heterocyclic ring system containing sulfur and nitrogen atoms, which may contribute to the compound's biological activity and stability.
Dimethylethoxy group
A substituent (-OCH3) attached to the ester linkage, which may influence the compound's lipophilicity and solubility in various solvents.
Dimethylethyl group
A substituent (-C(CH3)3) attached to the ester linkage, which may contribute to the compound's steric hindrance and stability.
Dimethylsilyloxy group
A substituent (-OSi(CH3)3) attached to the ester linkage, which may affect the compound's reactivity and stability, as well as its solubility in non-polar solvents.
Medicinal chemistry applications
Due to its diverse structural features, 1H-Indole-1-carboxylic acid,
2-[1-[(1,1-dimethylethoxy)carbonyl]-5-(3-methoxyphenyl)-1H-thieno[3,2-
c]pyrazol-3-yl]-6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, 1,1-dimethylethyl
ester may have potential applications in the design and development of new drugs, acting as a versatile building block for various therapeutic targets.
Pharmaceutical relevance
The compound's unique structure and functional groups may contribute to its potential use in the pharmaceutical industry, either as an active pharmaceutical ingredient or as a precursor for further chemical modifications.
Check Digit Verification of cas no
The CAS Registry Mumber 848357-91-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,8,3,5 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 848357-91:
(8*8)+(7*4)+(6*8)+(5*3)+(4*5)+(3*7)+(2*9)+(1*1)=215
215 % 10 = 5
So 848357-91-5 is a valid CAS Registry Number.
848357-91-5Relevant academic research and scientific papers
THIENOPYRAZOLES
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Page/Page column 104; 107-108, (2008/06/13)
Thienopyrazoles, their preparation, pharmaceutical compositions comprising these compounds, and their pharmaceutical uses in the treatment of disease states capable of being modulated by the inhibition of the protein kinases, in particular interleukin-2 inducible tyrosine kinase (ITK).
