848473-87-0

Upstream product

• 102359-00-2 2-oxoindoline-5-carboxylic acid 
• 6850-57-3 2-methoxybenzylamine 
• 848472-20-8 N-(2-methoxybenzyl)-2-oxoindoline-5-carboxamide 
• 64614-53-5 1-(6-chloro-pyridine-3-sulfonyl)-4-methyl-piperazine 

Downstream Products

• 848473-86-9 2-hydroxy-N-(2-methoxybenzylamide)-3-{5-[(4-methylpiperazin-1-yl)sulfonyl]pyridin-2-yl}-1H-indole-5-carboxamide hydrochloride 

Relevant academic research and scientific papers

NEW COMPOUNDS

The present invention relates to new compounds of formula Ia or Ib wherein P represents a 5- or 6-membered heteroaromatic ring containing one or two heteroatoms selected independently from N, O and S of which at least one heteroatom is nitrogen; R is hydrogen; R is selected from: C1-6alkyl, cyano, halogen, (CO)OR, and CONRR; R is selected from: C1-6alkyl, cyano, nitro, (CO)OR, C1-6alkylNRR, OC2-6alkylNRR, CONRR, and (SO2)NRR; m is 0, 1, 2, 3 or 4; n is 0, 1, 2, 3 or 4; as a free base or a salt thereof, a process for their preparation and new intermediates used therein, pharmaceutical formulations containing said therapeutically active compounds and to the use of said active compounds in therapy.