848609-24-5Relevant academic research and scientific papers
Studies on acyclic pyrimidines as inhibitors of mycobacteria
Srivastav, Naveen C.,Manning, Tracey,Kunimoto, Dennis Y.,Kumar, Rakesh
, p. 2045 - 2053 (2007)
In vitro anti-mycobacterial activities of several 5-substituted acyclic pyrimidine nucleosides containing 1-(2-hydroxyethoxy)methyl and 1-[(2-hydroxy-1-(hydroxymethyl) ethoxy)methyl] acyclic moieties are investigated against three mycobacteria viz. Mycoba
Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series
Amblard, Franck,Aucagne, Vincent,Guenot, Pierre,Schinazi, Raymond F.,Agrofoglio, Luigi A.
, p. 1239 - 1248 (2007/10/03)
The synthesis of novel acyclic nucleosides in the 5-alkynyl and 6-alkylfuro[2,3-d]pyrimidine series is described. These compounds were evaluated against HIV and HSV in order to determine their spectrum of antiviral activity. Their cytotoxicities against P
