848645-06-7

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 22518-00-9 1-[2-hydroxy-4-(hydroxymethyl)phenyl]ethan-1-one 
• 848566-04-1 1-[2-acetoxy-4-(bromomethyl)phenyl]ethan-1-one 
• 112920-14-6 2-acetoxy-4-methylacetophenone 

Downstream Products

• 848566-05-2 6-methyl-2-[2-(triisopropylsilanyloxy)-4-(triisopropylsilanyloxymethyl)phenyl]hept-5-en-2-ol 
• 848566-06-3 4-dimethyloxiranyl-2-[2-(triisopropylsilanyloxy)-4-(triisopropylsilanyloxymethyl)phenyl]butan-2-ol 

Relevant academic research and scientific papers

Isolation, structural elucidation, and synthesis of curcutetraol

The new natural products (+)-curcutetraol and (-)-curcutriolamide were isolated from the bacterium CNH-741 and the fungus CNC-979, isolated from marine sediment. (+)-Curcutetraol is a polar compound and contains a tertiary benzylic alcohol moiety at the single stereogenic center, which was retained without racemization by avoiding chromatography on silica. The absolute configuration of (+)-curcutetraol was determined by comparison of its experimental CD spectrum with the spectra predicted by quantum-chemical CD calculations. Phenolic bisabolane sesquiterpenoids from marine sources were previously known only from gorgonians and sponges. A short total synthesis of racemic curcutetraol has been developed. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.