848648-99-7Relevant academic research and scientific papers
Rational design, synthesis, and structure-Activity relationships of aryltriazoles as novel corticotropin-releasing factor-1 receptor antagonists
Lowe, Richard F.,Nelson, Jodene,Dang, Trunghau N.,Crowe, Paul D.,Pahuja, Anil,McCarthy, James R.,Grigoriadis, Dimitri E.,Conlon, Paul,Saunders, John,Chen, Chen,Szabo, Thomas,Chen, Ta Kung,Bozigian, Haig
, p. 1540 - 1549 (2007/10/03)
Following the discovery of the very high binding affinity of 4-anilinopyrimidines against corticotropin-releasing factor receptor-1 (CRF 1) (e.g., 1, Ki = 2 nM), a new series of triazoles bearing different groups has been synthesized
