84866-28-4

Upstream product

• 36060-85-2 (R)-N-acethylphenylglycine methyl ester 

Downstream Products

• 84866-30-8 (R)-Acetylamino-phenyl-acetyl azide 
• 1126635-28-6 5-methyl-2-(1-(N-acetylamino)-1-phenylmethyl)-1,3,4-oxadiazole 
• 1126635-27-5 2-(1-(N-Ac-amino)-1-phenylmethyl)-1,3,4-oxadiazole 
• 1126635-30-0 N-[1-phenyl-1-(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]acetamide 
• 1126635-29-7 5-ethyl-2-(1-(N-acetylamino)-1-phenylmethyl)-1,3,4-oxadiazole 
• 1227858-17-4 N-Ac-2-phenylglycine N'-ethoxymethylenehydrazide 
• 1227858-18-5 N-Ac-2-phenylglycine N'-(1-ethoxypropylidene)hydrazide 
• 84866-35-3 (R)-2-Acetylamino-N,N-dimethyl-2-phenyl-acetamide 
• 84866-36-4 (R)-((R)-2-Acetylamino-2-phenyl-acetylamino)-phenyl-acetic acid methyl ester 
• 84866-41-1 (R)-2-((R)-2-Ethylamino-2-phenyl-ethylamino)-2-phenyl-ethanol 
• 84866-34-2 (R)-2-Acetylamino-N-ethyl-2-phenyl-acetamide 
• 84866-39-7 (R)-N¹,N²-Diethyl-1-phenyl-ethane-1,2-diamine 
• 84866-40-0 (R)-N¹-Ethyl-N²,N²-dimethyl-1-phenyl-ethane-1,2-diamine 

Relevant academic research and scientific papers

An efficient synthesis of new 2-aminomethyl-1,3,4-oxadiazoles from enantiomeric phenylglycine hydrazides

New derivatives of 2-aminomethyl-1,3,4-oxadiazole were synthesized in the reactions of N-protected phenylglycine hydrazides and triethyl orthoesters (orthoformate, orthoacetate, orthopropionate, orthobenzoate) in the presence of glacial acetic acid. Studies on the cleavage reactions of the acid-sensitive N-BOC and N-Ac 1,3,4-oxadiazoles are presented. Spectral characteristics of the compounds and attempts to elucidate the racemization phenomenon observed in products are also discussed.