1126635-29-7Relevant academic research and scientific papers
N-protected N2-ethoxymethylene phenylglycine hydrazides as precursors of 1,3,4-oxadiazole derivatives
Kudelko, Agnieszka,Zielinski, Wojciech
experimental part, p. 883 - 896 (2010/10/02)
New derivatives of N2-ethoxymethylene phenylglycine hydrazide protected at the amino group by acetyl and tert-butoxycarbonyl were synthesized with reactions of N-protected phenylglycine hydrazides andtriethyl orthoesters. They underwent cycliza
An efficient synthesis of new 2-aminomethyl-1,3,4-oxadiazoles from enantiomeric phenylglycine hydrazides
Kudelko, Agnieszka,Zieliński, Wojciech
experimental part, p. 1200 - 1206 (2009/04/10)
New derivatives of 2-aminomethyl-1,3,4-oxadiazole were synthesized in the reactions of N-protected phenylglycine hydrazides and triethyl orthoesters (orthoformate, orthoacetate, orthopropionate, orthobenzoate) in the presence of glacial acetic acid. Studies on the cleavage reactions of the acid-sensitive N-BOC and N-Ac 1,3,4-oxadiazoles are presented. Spectral characteristics of the compounds and attempts to elucidate the racemization phenomenon observed in products are also discussed.
