84869-39-6

Usage

InChI:InChI=1/C12H8N4O4/c1-4-2-6-7(3-5(4)11(18)19)14-9-8(13-6)10(17)16-12(20)15-9/h2-3H,1H3,(H,18,19)(H2,14,15,16,17,20)

Upstream product

• 101750-71-4 7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydro-benzo[g]pteridine-8-carboxylic acid 
• 61066-33-9 pyrimidine-2,4,5,6(1H,3H)-tetraone 
• 86139-87-9 4,5-diamino-2-methylbenzoic acid 
• 101084-64-4 2-methyl-4,5-dinitro-benzoic acid 
• 1975-51-5 2-methyl-4-nitrobenzoic acid 
• 1088-56-8 lumiflavin 

Relevant academic research and scientific papers

PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS

Photoactive probes and probe systems for detecting biological interactions are described. The photoactive probes include probes that combine both photocleavable and photoreactive moieties. The photoactive probe systems can include a first probe comprising a photocatalytic group and a second probe comprising a group that can act as a substrate for the reaction catalyzed by the photocatalytic group. The probes and probe systems can also include groups that can specifically bind to a binding partner on a biological entity of interest and a detectable group or a precursor thereof. The probes and probe systems can detect spatiotemporal interactions of proteins or cells. In some embodiments, the interactions can be detected in live cells. Also described are methods of detecting the biological interactions.