848691-95-2

Upstream product

• 848691-91-8 (Z)-5-(tert-butyldiphenylsilyl)oxy-3-methyl-1-trimethylsilyl-3-penten-1-yne 
• 360768-07-6 (Z)-3-bromo-5-(tert-butyldiphenylsilyl)oxy-1-trimethylsilyl-3-penten-1-yne 
• 74-88-4 methyl iodide 
• 848691-94-1 (Z)-5-(tert-butyldimethylsilyl)oxy-3-methyl-3-pentenoic acid 

Downstream Products

• 856410-37-2 (2E,5Z)-(1R)-7-(tert-butyldiphenylsilyl)oxy-1-{(4R,5S)-2,2-dimethyl-5-[2-(4-methoxybenzyloxy)ethyl]-[1,3]-dioxolan-4-yl}-5-methyl-hepta-2,5-dien-1-ol 
• 856410-50-9 (2E,5Z)-7-(tert-butyldiphenylsilyl)oxy-1-{(4R,5S)-2,2-dimethyl-5-[2-(4-methoxybenzyloxy)ethyl]-[1,3]-dioxolan-4-yl}-5-methyl-hepta-2,5-dien-1-one 
• 848691-92-9 (Z)-5-(tert-butyldimethylsilyl)oxy-3-methyl-3-penten-1-al 
• 856410-39-4 (S)-2-((E)-2-{(4S,5S)-5-[2-(4-Methoxy-benzyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-vinyl)-4-methyl-3,6-dihydro-2H-pyran 
• 223458-11-5 (3Z)-5-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-3-methylpent-3-enol 

Relevant academic research and scientific papers

Stereoselective preparation of trisubstituted (Z)-alkenes; synthesis of the C17-C27 fragment of (-)-laulimalide

A Ni-catalyzed cross-coupling reaction of (Z)-5-(tert-butyldiphenylsilyl) oxy-3-bromo-1-trimethylsilyl-3-penten-1-yne (1) with alkyl Grignard reagent gives (Z)-3-alkyl-5-(tert-butyldiphenylsilyl)oxy-1-trimethylsilyl-3-penten-1- ynes (2) stereospecifically