848762-49-2Relevant academic research and scientific papers
Biomimetic total synthesis of gambogin and rate acceleration of pericyclic reactions in aqueous media
Nicolaou,Xu, Hao,Wartmann, Markus
, p. 756 - 761 (2007/10/03)
A significant rate acceleration of a Claisen rearrangement and of a Claisen/Diels-Alder reaction cascade sequence was observed in the presence of water. This reaction sequence was used in a total synthesis of gambogin (1) from a tricyclic dialkene 3 via 2
